1. Durvalumab (Imfinzi®): It is a monoclonal antibody that inhibits programmed death ligand 1 (PD-L1). Durvalumab is a human immunoglobulin G1κ (IgG1κ) monoclonal antibody. It is produced by using recombinant DNA technology in Chinese hamster ovary (CHO) cells which cultured in suspension. The expression of PD-L1 may be induced by inflammatory signals (such...
Sunday, December 29, 2024
Sunday, September 29, 2024
What are the functions of various B vitamins?🔢🔢🔢

There are many kinds of vitamin B, such as vitamin B1, B2, B6, and B12. They all work in different ways and can relieve many different symptoms. They will be introduced one by one below.1. Vitamin B1:Alcoholics should supplement in appropriate amounts.Vitamin B1 is also called thiamine. Long-term alcohol consumption can cause vitamin B1 deficiency. Beriberi is another...
Thursday, August 1, 2024
What are the characteristics of pregabalin?📄📄📄

Pregabalin is a drug used to treat neuropathic pain. Clinically, it is widely used to treat post-herpetic neuralgia, neuralgia caused by diabetic neuropathy, etc.What are the clinical indications for pregabalin?Pregabalin is clinically approved for the treatment of diabetic peripheral neuropathy, fibromyalgia, neuralgia associated with spinal cord injury, partial seizures...
Sunday, June 30, 2024
What is the difference between azivudine, monogravir and nematvir/ritonavir?💫💫💫

Azivudine, monogravir and nematvir/ritonavir are all clinical drugs used to treat the new coronavirus. What's the difference between them? What is the anti-coronavirus mechanism?The new coronavirus is composed of RNA and protein. The raw material for RNA synthesis is cytosine nucleoside. Azivudine and monogravir are cytosine nucleoside analogs. They will synthesize poor...
Sunday, May 26, 2024
What is the difference between acetaminophen and ibuprofen?👀👀👀

Acetaminophen and ibuprofen are very commonly used antipyretic and analgesic drugs in clinical practice. However, their chemical structure, intensity of action and adverse reactions will differ. Will there be any difference in clinical use?Difference in effectiveness of acetaminophen and ibuprofen.The analgesic and antipyretic effect of ibuprofen is slightly stronger than...
Monday, April 22, 2024
When should lipid-lowering drugs be taken?⌚⌚⌚

Dyslipidemia generally refers to elevated levels of cholesterol and/or triglycerides (TG) in the blood. It is also called hyperlipidemia. At the same time, it also includes various dyslipidemias including low high-density lipoprotein cholesterol (HDL-C). The main clinical lipid-lowering drugs currently include cholesterol absorption inhibitors, HMG-CoA inhibitors (statins),...
Wednesday, January 17, 2024
Basic knowledge about febuxostat.📃📃📃

Febuxostat is a xanthine oxidase inhibitor. It inhibits the production of uric acid. While allopurinol can only inhibit the reduced form of xanthine oxidase, febuxostat can inhibit both the reduced and oxidized forms of xanthine oxidase. Therefore, febuxostat's ability to lower uric acid is faster and stronger. 80% of blood uric acid is synthesized in the body, and only...
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An introduction to Nivolumab (Opdivo®) and its common usage and dosage.(Part 1)👀👀👀
Nivolumab (Opdivo®) is a monoclonal antibody. It binds to the PD-1 receptor, thereby blocking the interaction of the PD-1 receptor with PD-...