An introduction to Ipilimumab (Yervoy®) and its common usage and dosage.👀👀👀

Ipilimumab (Yervoy®) is a cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) immune checkpoint inhibitor. It is a monoclonal antibody that binds to CTLA-4 and inhibits the interaction between CTLA-4 and its ligands CD80/CD86. It blocks T cell inhibitory signals induced by the CTLA-4 pathway, thereby increasing the number of active effector T cells. These T cells will...

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An introduction to Atezolizumab (Tecentriq®) and its common usage and dosage.👀👀👀

Programmed death ligand 1 (PD-L1) may be expressed on tumor cells and/or tumor-infiltrating immune cells. It promotes the suppression of antitumor immune responses in the tumor microenvironment. PD-L1 binds to the PD-1 and B7.1 receptors on T cells and antigen-presenting cells. The activity, proliferation and cytokine production of cytotoxic T cells are thereby inhibited....

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