An introduction to Nivolumab (Opdivo®) and its common usage and dosage.(Part 2)👀👀👀

The introduction to Nivolumab (Opdivo®) Part. 2. Nivolumab is recommended for the treatment of a variety of malignancies in children aged 12 years and older.Common Pediatric Usage and Dosage of Nivolumab:Recommended dose of nivolumab monotherapy: Indications Dosage Duration Unresectable or metastatic melanoma For pediatric patients...

Read More

An introduction to Nivolumab (Opdivo®) and its common usage and dosage.(Part 1)👀👀👀

Nivolumab (Opdivo®) is a monoclonal antibody. It binds to the PD-1 receptor, thereby blocking the interaction of the PD-1 receptor with PD-L1 and PD-L2. Immunosuppressive responses mediated by the PD-1 pathway will be blocked (such as tumor immune responses). Nivolumab can be used to treat a variety of malignant tumors in adults. Nivolumab is commonly used in the form...

Read More

An introduction to Ipilimumab (Yervoy®) and its common usage and dosage.👀👀👀

Ipilimumab (Yervoy®) is a cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) immune checkpoint inhibitor. It is a monoclonal antibody that binds to CTLA-4 and inhibits the interaction between CTLA-4 and its ligands CD80/CD86. It blocks T cell inhibitory signals induced by the CTLA-4 pathway, thereby increasing the number of active effector T cells. These T cells will...

Read More

An introduction to Atezolizumab (Tecentriq®) and its common usage and dosage.👀👀👀

Programmed death ligand 1 (PD-L1) may be expressed on tumor cells and/or tumor-infiltrating immune cells. It promotes the suppression of antitumor immune responses in the tumor microenvironment. PD-L1 binds to the PD-1 and B7.1 receptors on T cells and antigen-presenting cells. The activity, proliferation and cytokine production of cytotoxic T cells are thereby inhibited....

Read More

An introduction to Avelumab (Bavencio®) and its common usage and dosage.👀👀👀

Avelumab (Bavencio®): It is a Programmed Death Ligand 1 (PD-L1) inhibitor that was first approved by the FDA in 2017. Programmed Death Ligand 1 is expressed on tumor cells and immune cells infiltrating tumors. It suppresses anti-tumor immunity in the tumor microenvironment. PD-1 and B7.1 receptors on T cells and antigen-presenting cells bind to PD-L1. They inhibit...

Read More

An introduction to Durvalumab (Imfinzi®) and its common usage and dosage.👀👀👀

1. Durvalumab (Imfinzi®): It is a monoclonal antibody that inhibits programmed death ligand 1 (PD-L1). Durvalumab is a human immunoglobulin G1κ (IgG1κ) monoclonal antibody. It is produced by using recombinant DNA technology in Chinese hamster ovary (CHO) cells which cultured in suspension. The expression of PD-L1 may be induced by inflammatory signals (such...

Read More