Can we smoke when taking medicines???💣💣💣

 Smoking (Most drugs)

For most drugs, we should not smoke at least 30 minutes before and after taking the drug. For some drugs, such as aminophylline, the dosages need to be adjusted after you quit smoking.

In flue-cured cigarettes, The amount of tar is about 11mg. Some substances in tar can induce the drug-metabolizing enzymes in liver, such as CYP1A1, CYP1A2, CYP2E1. It will promote the metabolism of drugs (For example, it increases the clearance rate of aminophylline by 58-100%), and significantly reduce the efficacy of drugs.

The amount of nicotine is about 1mg in flue-cured cigarettes. Nicotine is mainly metabolized by the drug-metabolizing enzymes in liver (CYP2A6). And the drugs (such as Methoxsalen) reduce the metabolism of nicotine by inhibiting CYP2A6. It causes dizziness, headache, nausea, vomiting, and even severe arrhythmia.

Especially when you are taking below drugs:

Antipyretic analgesics: such as Acetaminophen

Anticoagulants: such as Warfarin

Antipsychotics: such as Mirtazapine

Antiarrhythmic drugs: such as Mexiletine

Antiasthmatic drugs: such as Theophylline

Adrenergic receptor agonists and blockers: such as Metoprolol

Antihypertensive drugs: such as Nifedipine

Hypoglycemic drugs: such as Insulin

Other drugs

For women who taking oral contraceptives, the incidence and death rate of myocardial infarction in smokers are 10 times higher than non-smokers of the same age.

***For your health, quit smoking please~😁