In general, almost all medicines are taken with water. However, the amount of drinking water is various when taking different medicines. There are some medicines require drinking a lot of water. Most of medicines taken by the human body are eliminated by the kidneys. Drinking plenty of water when taking medicines can reduce the burden on the kidneys, excrete toxins and enhance metabolism of medicines. The following types of drugs should be noted to drink a lot of water when taking:
1. Antipyretic and analgesic
When you have a cold and you are taking antipyretic and analgesics, you should drink more water. Your urine output should not be less than 1.5 liters per day. You should pay more attention when you have a high fever or in summer. First of all, since these drugs can irritate the stomach at high concentrations, this irritation can be reduced by drinking more water. In addition, drinking water during a cold helps the body to urinate a lot to metabolize toxins in the body. Finally, antipyretic drugs have the effect of reducing fever and sweating occurs during the process of reducing fever. When sweat evaporates, it can take away a large amount of body temperature and water, thereby returning body temperature to normal. It is necessary to properly supplement water. If you drink too little water, it is not conducive to sweating and reducing fever. It will also cause collapse because the body's water is not replenished in time.
2. Antibacterial drugs
Aminoglycoside antibiotics: such as amikacin, gentamicin, etc. Aminoglycoside antibiotics are highly toxic to the kidneys. The higher the concentration, the greater damage to the renal tubules. Therefore, it is advisable to drink more water to dilute and accelerate the excretion of the drug.
Sulfonamide antibacterial drugs: Sulfonamide drugs and their metabolites are mainly excreted through the kidneys. Sometimes they precipitate out from the urine and form crystals, causing low back pain, proteinuria and hematuria. In severe cases, the crystals can block the urinary tract and obstruct urine excretion. Drinking a lot of water can increase urine output and reduce the concentration of drugs in the urine. It can also combine with some drugs that can alkalize urine at the same time, such as sodium bicarbonate, to avoid precipitation of crystals and damage the kidneys.
Quinolone antibacterial drugs: such as levofloxacin, ciprofloxacin, etc., are mainly excreted through the kidneys. Crystal urine may occur when large doses of fluoroquinolones are used or the urine pH is above 7. In order to avoid the occurrence of crystal urine, you should drink more water and maintain a 24-hour urine output above 1200ml.
3. Antiviral drugs
Antiviral drugs such as acyclovir and famciclovir can cause crystalline renal failure. Therefore, it is advisable to drink more water during the medication period, especially the elderly. Due to the decline of physiological renal function, the dosage should be reduced. Combined use with zidovudine can cause nephrotoxicity. It manifests as fatigue, deep lethargy. It also competitively inhibit the secretion of organic acids with probenecid, which can slow down the excretion of this class of drugs. It will accumulate the amount of drugs in the body.
4. Anti-gout drugs
When you are taking anti-gout drugs such as benzbromarone, allopurinol, etc., you should drink more water and ensure that the drinking amount is not less than 2 liters. It can reduce the irritation to the digestive tract. At the same time, enough water can alkalize the urine to prevent the formation of stones in the urinary tract during the excretion of uric acid.
5. Bisphosphate
Bisphosphonates such as alendronate sodium, clodronate disodium, etc. In the treatment of hypercalcemia, bisphosphonates can cause electrolyte disturbance and water loss. Therefore, you should pay attention to supplement body fluids and make the daily urine output reaching more than 2000ml. Bisphosphonates are also very irritating to the gastrointestinal tract. Drinking plenty of water when taking it can help reduce the irritation of bisphosphonates to the gastrointestinal tract. In addition, it is not advisable to lie down immediately after taking the medicine and keep the upper body upright for at least 30 minutes (Ibandronate should keep the upper body upright for 60 minutes).
πIn addition to drinking plenty of water when taking these drugs, you should also drink enough water at ordinary times.
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