The use of oral ibuprofen and its precautions.😎😎😎

Ibuprofen is an antipyretic and analgesic which is commonly used clinically. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It inhibits cyclooxygenase, reduces the synthesis of prostaglandins and produces analgesic and anti-inflammatory effects. It has an antipyretic effect through the hypothalamic body temperature regulation center.

Ibuprofen precaution for children:

Rectal temperature ≥ 39.0°C, oral temperature ≥ 38.5°C, axillary temperature ≥ 38.2°C or fever children who are uncomfortable and depressed due to fever. Ibuprofen or acetaminophen is recommended.

Acetaminophen can be used for children ≥ 2 months and ibuprofen can be used for children ≥ 6 months. Acetaminophen combined with ibuprofen is not recommended for children's fever nor alternate acetaminophen and ibuprofen.

The dose of oral ibuprofen for children is 10mg/kg each time. The shortest interval is 6-8 hours and no more than 4 times within 24 hours. If symptoms are not relieved after taking it for three consecutive days, see a doctor as soon as possible.

Ibuprofen precaution for adults:

1. Anti-arthritis: 0.4g-0.6g each time, 3-4 times a day, the dosage of rheumatoid arthritis is larger than osteoarthritis.

2. Mild to moderate pain: 0.2-0.4g each time every 4-6 hours. The maximum daily dose is 2.4g.

Ibuprofen can weaken the antiplatelet effect of low-dose aspirin. Patients who are taking low-dose aspirin should not use ibuprofen. Use acetaminophen instead of ibuprofen.

Ibuprofen precaution for breastfeeding women:

When breastfeeding women take ibuprofen, no serious adverse reactions have been found in the breastfed infants. The intake of ibuprofen by the breastfed infants is 0.0008% of the mother's dose. Lactating women can use ibuprofen with caution.

Ibuprofen precaution for pregnant women:

Taking ibuprofen in early pregnancy can cause cardiovascular malformations and cleft palate. Taking ibuprofen in late pregnancy can lead to unclosed arterial ducts and myocardial degenerative changes. Therefore, pregnant women should not use ibuprofen.

Common side effects:

Common side effects are nausea, dyspepsia, gastric ulcer bleeding and allergic reactions. Long-term use of ibuprofen can cause kidney damage, bleeding and increase the risk of cardiovascular disease.

It can be taken with food to avoid indigestion or stomach irritation.